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Auto Immune

Game overview

Auto Immune

A virus is attacking your cells, and its up to you to defend them! Buy and combine cells to assemble your immune response. Discover powerful synergies to overcome a constantly evolving enemy in this physics-based auto battler. Can you achieve IMMUNITY?

Casual Strategy Early Access
Last tracked players
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About this game Read the full description
A virus is attacking your cells, and its up to you to defend them! Buy and combine cells to assemble your immune response. Discover powerful synergies to overcome a constantly evolving enemy in this physics-based auto battler. Build an ironclad immune defense in 10 turns or perish.

Create the ultimate immune response


Create the ultimate immune response: Combine immune cells in interesting ways to overcome incoming pathogens. Merging the same immune cells together will strengthen them and can unlock higher tier immune cells to experiment with. Chaining different cells together can reveal powerful synergies.

Adapt or die:


Adapt or die: Viruses will multiply each turn and become an even bigger threat! You’ll adapt to the current situation and form the best defense given limited resources.

Outlive or Outlast


In single player mode, the objective of the game is to make it to turn 12. In asynchronous multiplayer mode you win by outlasting the replays from other player's games and gain rank.

If you made this far...

You made it past the fold! You deserve a reward. Here are a few tips to make sure you can get the most out of the game as quickly as possible!

Basics Tips:
  • You CANNOT destroy the Infected cells that spawn viruses. Focus on defending against the viruses.
  • You can rotate cells if you grab and drag the black arrow that appears after placing them
  • Cells cost money ("Carbs")! You start with 4 and gain one every turn. You lose any money you don't spend at the end of your turn.
  • Everything resets after every Infection round, unless it says otherwise. Damage is not persistent between rounds!

Intermediate Tips:
  • Try to spend all your money each turn! Its use it or lose it unless you have a cell that works on unspent money.
  • You can combine any two cells with the same name. Combining two has double the health. But combine 3 and it becomes
    an elite cell (which is usually as strong as 2 non-elites) and allows to choose a Reward cell.
  • Reward cells are some of the strongest in the game! So don't miss out on combining as this is the only way to get them.
  • You CAN move your Blood Cells. This can give you a lot more space to work with!
  • Viruses can open attack lanes from any direction except directly down.
  • But they will only open a maximum of 3 lanes, including the first one which always attacks from the right.

Player activity

Concurrent players over the last 48 hours.

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Auto Immune is at Steam Tower Defense Festival Crafting the perfect immune response - Auto Immune Dev Stream Auto Immune in Steam Next Fest
System requirements Windows

Windows

Minimum

Minimum:
  • OS *: 64-bit Windows 7 / 8 / 10 / 11
  • Processor: Intel i5, 2.4 Ghz or better
  • Memory: 4 GB RAM
  • Graphics: Integrated HD Graphics 520 w/128 MB or better
  • Network: Broadband Internet connection
  • Storage: 1 GB available space
  • Sound Card: DirectX Compatible Sound Card
Game details Languages, features & support
Publisher
Distant Signal Games
Brazilian rating
6
Steam Germany rating
12
Features
Single-player, Multi-player, Steam Achievements, Family Sharing
Languages
English
Compatibility & accessibility Steam Deck, controllers & access features

Can I Play This?

Steam declarations and Valve's Steam Deck compatibility result. Missing data is shown as unknown, never unsupported.

Some source data is stale
Native Steam builds
Windows: unknown
macOS: unknown
Linux: unknown
Steam Deck
unknown
Valve compatibility test
Input
Controller support: unknown
Structured language support (1)
LanguageInterfaceFull audioSubtitles
EnglishYesNoNo
Steam store page stale · checked 2026-09-04 PCGamingWiki technical notes External link only; SteamIQHQ does not ingest PCGamingWiki content.
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Early Access Abandoned

Time in EA
193 days
Updates
8

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Frequently Asked Questions

Is Auto Immune free to play?
Yes, Auto Immune is free to play on Steam.
What genre is Auto Immune?
Auto Immune is a Casual, Strategy, Early Access game.
Who developed Auto Immune?
Auto Immune was developed by Distant Signal Games and published by Distant Signal Games.
What platforms does Auto Immune support?
Available on Steam for Windows.