S.E.M.I. – Side Effects May Include...
S.E.M.I. – Side Effects May Include... - Steam Charts & Historical Stats
A fun cooperative action game for 1-4 players about escaping from a special clinic. Explore historical player activity and pricing for S.E.M.I. – Side Effects May Include.... Player-count data was last observed Apr 30, 2026.
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S.E.M.I. - Demo Trailer
S.E.M.I. - Teaser
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System Requirements
- Requires a 64-bit processor and operating system
- OS: Windows 10
- Processor: Intel Core i5 series or Ryzen series
- Memory: 8 GB RAM
- Graphics: GTX 960 or AMD R9 290
- DirectX: Version 11
- Storage: 3 GB available space
- Requires a 64-bit processor and operating system
- OS: Windows 11
- Processor: Intel Core i7 series or Ryzen series
- Memory: 8 GB RAM
- Graphics: GTX 1660 or RX6600
- DirectX: Version 12
- Storage: 3 GB available space
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About This Game
A fun cooperative action game for 1-4 players about escaping from a special clinic. Become a patient, take experimental drugs, get superpowers… And unpredictable side effects!
Detailed Description
S.E.M.I. is a cooperative online game about escaping from a special clinic. Here you and up to 3 of your feeble-minded loyal friends in the role of patients fight with the staff and other patients and find yourself in unexpected situations. Teamwork is essential, as randomized events and experimental drugs will lead your party into unpredictable mayhem. Pop pills with your friends as you cooperate to gain your freedom.
Communicate in voice chat and arrange sabotage help your friends pass through rooms, get out of traps and fight with opponents! In your arsenal: close combat, physics, amazing abilities and ... imagination!
Take pills and get abilities:
Bipolar force is an invulnerable monster, then a helpless rag!
Laser astigmatism — two sights, one laser… Where will he shoot?
Stendhal syndrome — are you looking at a painting? Now you're hysterical and destroying everything around you!
Alice's syndrome is either tiny or gigantic — have time to adjust!
Madness is near! You and your friends can go crazy and start running, jumping and fighting, and your abilities will become uncontrollable. Do you want to take back control? Take the pills :)
Locations are randomly generated from rooms with changing gravity, traps, moving walls, and other "pleasant" surprises.
After a successful escape, you will receive a medical report: "The patient was stable until he started hitting the guards with a bottle. Diagnosis: Overmotivation" or something worse!
Unlock new costumes and decorations. Let each new escape be more stylish than the previous one!
Will you and your friends be able to escape... or at least not go crazy?
Welcome to the mental hospital! Here, your abilities are a lottery, and your friends can be the most dangerous opponents!