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Against the Gradient

Game overview

Against the Gradient

Cogent Education · Jul 10, 2017

A microscopic world is in need of your help! Add transporters to membranes to move molecules and ions into and out of cells. Your goal is to reach specific concentrations.

Education Puzzle Science Mouse only Touch-Friendly
Last tracked players
0
All-time peak
Unavailable
24-hour change
Unavailable
Steam reviews
100% positive
2 reviews · via SteamSpy

Delayed observation · last tracked . Values marked unavailable are not estimated.

About this game Read the full description
A microscopic world is in need of your help! Add transporters to membranes to move molecules and ions into and out of cells. Your goal is to reach specific concentrations.

Over 20 unique puzzles will help you master the principles of cellular transport. Use channels, co-transporters, and antiporters to master facilitated diffusion and active transport.

Think you understand how transporters diffuse molecules and ions across the membrane? Try making your own puzzles with the built in level editor!

Features:
  • Over 20 puzzles ranging from a gentle introduction to challenging mind benders.
  • Speed up and slow down time to play at your own pace.
  • 16 transporters including real proteins found in your body and imaginative nano-robots.
  • Puzzle mechanics based on real biological principles of cellular transport.
  • Built-in level editor lets you take control and make your own levels to challenge your friends!
Media gallery 5 screenshots · 0 videos
Against the Gradient game capsule image

Screenshots

Against the Gradient screenshot 1
Against the Gradient screenshot 2
Against the Gradient screenshot 3
Against the Gradient screenshot 4
Against the Gradient screenshot 5

Player activity

Concurrent players over the last 48 hours.

Loading player history?
System requirements Windows · macOS · Linux

Windows

Minimum

Minimum:
  • OS *: Windows XP SP2+
  • Processor: SSE2 instruction set support.
  • Memory: 1 GB RAM
  • Graphics: DX9 (shader model 2.0) capabilities; generally everything made since 2004 should work.
  • Storage: 100 MB available space

macOS

Minimum

Minimum:
  • OS: Mac OS X 10.8+
  • Processor: SSE2 instruction set support.
  • Memory: 1 GB RAM
  • Graphics: DX9 (shader model 2.0) capabilities; generally everything made since 2004 should work.
  • Storage: 100 MB available space

Linux

Minimum

Minimum:
  • OS: Ubuntu 12.04+, SteamOS+
  • Processor: SSE2 instruction set support.
  • Memory: 1 GB RAM
  • Graphics: DX9 (shader model 2.0) capabilities; generally everything made since 2004 should work.
  • Storage: 100 MB available space
Game details Languages, features & support
Publisher
Cogent Education
Achievements
22
Features
Single-player, Steam Achievements, Steam Cloud, Includes level editor, Family Sharing
Languages
English
Compatibility & accessibility Steam Deck, controllers & access features

Can I Play This?

Steam declarations and Valve's Steam Deck compatibility result. Missing data is shown as unknown, never unsupported.

Sources fresh
Native Steam builds
Windows: unknown
macOS: unknown
Linux: unknown
Steam Deck
unknown
Valve compatibility test
Input
Controller support: unknown
Structured language support (1)
LanguageInterfaceFull audioSubtitles
EnglishYesNoNo
Steam store page fresh · checked 2026-10-17 PCGamingWiki technical notes External link only; SteamIQHQ does not ingest PCGamingWiki content.
Achievement progress Rarity & completion patterns

Achievement Difficulty

Global unlock percentages are not exact completion or retention metrics.

Steam source
Achievements measured
22
Hunter score
52.3 / 100
SteamIQHQ inference from rarity and count
Progression analysis
Achievement rarity is available, but milestone order is not defensible.

Rarest achievements

Last but not least 11.7%
Anti-co-operation 12.2%
Hard Times 12.7%
Heavy Lifter 12.7%
All together now 13.6%

Difficulty distribution

Ultra rare (<1%)0
Very rare (1–5%)0
Rare (5–20%)9
Uncommon (20–50%)7
Common (50%+)6
Observed Nov 10, 2026 23:44 UTC · fresh
More analysis Activity patterns, updates & developer tools

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Game Insights

Buy Verdict

Watch — $2.99.

Decent deal at 0% off, but might drop further. Watch for better opportunities.

▲ ~13 days until next sale

Value Score

Great Value — 93th percentile.

Price-to-player ratio ranks in the 93th percentile. Priced as Market at $2.99.

▲ Market pricing tier

Genre Benchmarks

Value Ratio Top 7%

Activity Heatmap

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Developer Analytics

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Frequently Asked Questions

Is Against the Gradient worth buying right now?
Watch — $2.99. Decent deal at 0% off, but might drop further. Watch for better opportunities.
When does Against the Gradient go on sale?
Decent deal at 0% off, but might drop further. Watch for better opportunities.
Is Against the Gradient free to play?
Against the Gradient costs $2.99 on Steam.
What genre is Against the Gradient?
Against the Gradient is a Casual, Indie, Simulation game.
Who developed Against the Gradient?
Against the Gradient was developed by Cogent Education and published by Cogent Education.
What platforms does Against the Gradient support?
Available on Steam for Windows, macOS, Linux.

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